Plasmablastic lymphoma: current perspectives
نویسندگان
چکیده
منابع مشابه
Current knowledge on HIV-associated Plasmablastic Lymphoma
HIV-associated PBL is an AIDS-defining cancer, classified by WHO as a distinct entity of aggressive DLBCL. To date less than 250 cases have been published, of them 17 are pediatric. The pathogenesis of this rare disease is related to immunodeficiency, chronic immune stimulation and EBV. Clinically is a rapid growing destructive disease mainly involving the oral cavity even if extraoral and extr...
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BACKGROUND Plasmablastic lymphoma (PBL) is a B-cell malignancy associated with human immunodeficiency virus (HIV). PBL could also influence the HIV-negative patients. The study aimed to identify prognostic factors for survival among Chinese PBL patients. MATERIALS AND METHODS Eligible patients from literature and Peking Union Medical College Hospital (PUMCH) were included in this study. Clini...
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which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. A 54-year-old woman was admitted with compression fracture of thoracic vertebral bodies. Urine protein electro-phoresis revealed the presence of M protein and serum free κ/λ ratio was 0.01. Bone marrow aspiration (A) and biopsy (B) revealed diffuse infiltrat...
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Plasmablastic lymphoma (PBL) is an aggressive subtype of non-Hodgkin's lymphoma (NHL), which frequently arises in the oral cavity of human immunodeficiency virus (HIV) infected patients. PBL shows diffuse proliferation of large neoplastic cells resembling B-immunoblasts/plasmablasts, or with plasmacytic features and an immunophenotype of plasma cells. PBL remains a diagnostic challenge due to i...
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Posttransplant lymphoproliferative disorder is a serious complication following solid organ as well as hematopoietic stem cell transplantation due to prolonged immunosuppressive therapy. Plasmablastic lymphoma, although classically associated with HIV infection, has since been described in transplant patients as a variant of posttransplant lymphoproliferative disorder with varying clinical pres...
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ژورنال
عنوان ژورنال: Blood and Lymphatic Cancer: Targets and Therapy
سال: 2018
ISSN: 1179-9889
DOI: 10.2147/blctt.s142814